Cystathionine beta synthase
Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine: L-serine + L-homocysteine L-cystathionine + H2O CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds.
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Biological functions of hydrogen sulfideCBSLCBS (disambiguation)CBS (gene)CBS domainCLCN5Chromosome 21CystathionineCystathionine-b-synthaseCystathionine-beta-synthaseCystathionine-β-synthaseCystathionine Beta-SynthaseCystathionine b-synthaseCystathionine beta-synthaseCystathionine synthaseCysteineEC 4.2.1.22Gaseous signaling moleculesHomocysteineHomocystinuriaKidney ischemiaL-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)Lanthionine ketimineList of EC numbers (EC 4)List of MeSH codes (D08)List of genes mutated in cutaneous conditionsList of genetic disordersList of human protein-coding genes 1Magnesium transporterMetal transporter CNNM3MethionineMethylcysteine synthaseMethylenetetrahydrofolate reductase deficiencyMexican tetraMorpheeinStockholm formatThrombophiliaTranssulfuration pathwayVesicular monoamine transporter 1Vitamin B6
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Cystathionine beta synthase
Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine: L-serine + L-homocysteine L-cystathionine + H2O CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds.
has abstract
Cystathionine-β-synthase, also ...... ssociated with homocystinuria.
@en
Die Cystathionin-β-Synthase (C ...... urestoffwechsel beteiligt ist.
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β-Syntaza cystationinowa (β-cy ...... linicznie jako homocystynuria.
@pl
Цистатіонін-β-синтаза (К. Ф. 4 ...... родуктів — сульфіду водню та .
@uk
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InternetArchiveBot
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CAS number
date
August 2017
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fix-attempted
yes
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name
cystathionine beta-synthase
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comment
Cystathionine-β-synthase, also ...... ch cleave carbon-oxygen bonds.
@en
Die Cystathionin-β-Synthase (C ...... urestoffwechsel beteiligt ist.
@de
β-Syntaza cystationinowa (β-cy ...... linicznie jako homocystynuria.
@pl
Цистатіонін-β-синтаза (К. Ф. 4 ...... родуктів — сульфіду водню та .
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label
Beta-syntaza cystationinowa
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Cystathionin-β-Synthase
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Cystathionine beta synthase
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Цистатіонін-β-синтаза
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