Cystic fibrosis transmembrane conductance regulator
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (sp
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1980s in science and technology1989 in scienceABCC7ATP-binding cassette transporterATP-binding domain of ABC transportersAdeno-associated virusAggresomeAllergic bronchopulmonary aspergillosisAmilorideAminoglycosideArylsulfatase BAzoospermiaBatsheva KeremBiochemical cascadeBronchiectasisC12orf40CFMJCFTRCFTR(gene)CFTR (disambiguation)CFTR (gene)CFTR inhibitory factorCFTR proteinCFTRΔF508Calu-3Carbonic anhydrase 12CftrCftr(gene)Cftr (gene)Channel blockerChimpanzee genome projectChloride channelChloride channel openerCholeraCholera toxinCiliumCongenital absence of the vas deferensCrofelemerCystic Fibrosis Transmembrane Conductance Regulator
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Cystic fibrosis transmembrane conductance regulator
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (sp
has abstract
ABCC7, також регулятор трансме ...... : ВалінW: Триптофан Y: Тирозин
@uk
CFTR (ang. cystic fibrosis tra ...... bę genetyczną – mukowiscydozę.
@pl
CFTR, acrónimo de Cystic fibro ...... es corporales esté aumentada.
@es
Cystic fibrosis transmembrane ...... deferens and male infertility.
@en
Dans l'espèce humaine comme ch ...... te, des cellules épithéliales.
@fr
Der Cystic Fibrosis Transmembr ...... e des Vas deferens (CAVD) ist.
@de
El gen CFTR o Cystic fibrosis ...... veure si existeixen mutacions.
@ca
Il regolatore della conduttanz ...... reus, Pseudomonas aeruginosa).
@it
Трансмембранный регулятор муко ...... ивного транспорта ионов хлора.
@ru
منظم موصلية التليف الكيسي عبر ...... اريات، ويُشفر بواسطة جين CFTR.
@ar
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ABCC7, також регулятор трансме ...... транспортерів), а іонів хлору.
@uk
CFTR (ang. cystic fibrosis tra ...... bę genetyczną – mukowiscydozę.
@pl
CFTR, acrónimo de Cystic fibro ...... es corporales esté aumentada.
@es
Cystic fibrosis transmembrane ...... he developing vas deferens (sp
@en
Dans l'espèce humaine comme ch ...... asienne, et de l' (en) (CAVD).
@fr
Der Cystic Fibrosis Transmembr ...... e des Vas deferens (CAVD) ist.
@de
El gen CFTR o Cystic fibrosis ...... veure si existeixen mutacions.
@ca
Il regolatore della conduttanz ...... iche delle vie aeree. Queste c
@it
Трансмембранный регулятор муко ...... лка в плазматической мембране.
@ru
منظم موصلية التليف الكيسي عبر ...... اريات، ويُشفر بواسطة جين CFTR.
@ar
label
CFTR
@ca
CFTR
@es
CFTR
@pl
Cystic Fibrosis Transmembrane Conductance Regulator
@de
Cystic fibrosis transmembrane conductance regulator
@en
Gène et protéine CFTR
@fr
Regolatore della conduttanza transmembrana della fibrosi cistica
@it
Регулятор трансмембранной проводимости при муковисцидозе
@ru
Регулятор трансмембранної провідності при муковісцидозі
@uk
منظم موصلية التليف الكيسي عبر الغشاء
@ar