David John House was a historic home located at Lexington, Lafayette County, Missouri. It was built about 1848, and is a one-story, double-pen plan red brick dwelling with Greek Revival style detailing. It had historic frame additions and featured two frame porches with distinctive cut-out posts and scrollwork railings added in the 1870s-1880s. Also on the property was the contributing privy. It is no longer in existence. It was listed on the National Register of Historic Places in 1993.