David Owen Meltzer (born 1964) is a Professor of Medicine at the University of Chicago. He holds faculty appointments in the Department of Medicine, Department of Economics and the Harris School of Public Policy Studies. He is Chief of the Section of Hospital Medicine at the University of Chicago Medicine, and is the Director of the Center for Health and the Social Sciences (CHeSS), as well as the Director of the Urban Health Lab in Chicago, IL. In 2015 he was appointed a member of the faculty for the forthcoming Barack Obama Presidential Center which will be located in Chicago's South Side.