Deborah Fisher Wharton (1795 – 1888) was an American Quaker minister, suffragist, social reformer and proponent of women's rights. She was one of a small group of dedicated Quakers who founded Swarthmore College. She was a contemporary and friend of Lucretia Mott and had many of Mott's sympathies but did not actively pursue the women's rights cause, rather she was a proponent of liberal Quaker spirituality. She was also the mother of industrialist Joseph Wharton.