Denison House was a woman-run settlement house in Boston's old South Cove neighborhood. Founded in 1892 by the College Settlements Association, it provided a variety of social and educational services to neighborhood residents, most of whom were immigrants. Several notable women worked there, including Nobel Prize winner Emily Greene Balch, labor organizer Mary Kenney O'Sullivan, and pioneering aviator Amelia Earhart. The original site at 93 Tyler Street is a stop on the Boston Women's Heritage Trail.