The Desert Inn, also known as the D.I., was a hotel and casino on the Las Vegas Strip in Paradise, Nevada, which operated from April 24, 1950, to August 28, 2000. Designed by architect Hugh Taylor and interior design by Jac Lessman, it was the fifth resort to open on the Strip, the first four being El Rancho Vegas, The New Frontier, the still-operating Flamingo, and the now-defunct El Rancho (then known as the Thunderbird). It was situated between Desert Inn Road and Sands Avenue.