Discoidin domain
Discoidin domain (also known as F5/8 type C domain, or C2-like domain) is major protein domain of many blood coagulation factors. Blood coagulation factors V and VIII contain a C-terminal, twice repeated, domain of about 150 amino acids, which is often called "C2-like domain" (that is unrelated to the C2 domain). In the Dictyostelium discoideum (Slime mold) cell adhesion protein discoidin, a related domain, named discoidin I-like domain, DLD, or DS, has been found which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Similar domains have been detected in other extracellular and membrane proteins. In coagulation factors V and VIII the repeated domains compose part of a larger functional domain whi
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Discoidin domain
Discoidin domain (also known as F5/8 type C domain, or C2-like domain) is major protein domain of many blood coagulation factors. Blood coagulation factors V and VIII contain a C-terminal, twice repeated, domain of about 150 amino acids, which is often called "C2-like domain" (that is unrelated to the C2 domain). In the Dictyostelium discoideum (Slime mold) cell adhesion protein discoidin, a related domain, named discoidin I-like domain, DLD, or DS, has been found which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Similar domains have been detected in other extracellular and membrane proteins. In coagulation factors V and VIII the repeated domains compose part of a larger functional domain whi
has abstract
Discoidin domain (also known a ...... d FA58C domain in MFGM Q08431.
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Symbol
F5_F8_type_C
Wikipage page ID
14,683,611
page length (characters) of wiki page
Wikipage revision ID
997,984,925
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caption
Structure of the membrane-binding C2 domain of factor VIII.
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CDD
cd00057
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InterPro
IPR000421
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name
F5/8 type C domain
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OPM family
OPM protein
Pfam
PF00754
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PROSITE
PDOC00988
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symbol
F5_F8_type_C
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wikiPageUsesTemplate
hypernym
comment
Discoidin domain (also known a ...... a larger functional domain whi
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label
Discoidin domain
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