Domingo Ortiz de Rozas (1721 – 1785) was a Spanish nobleman, who served in the Royal Guards at the service of the Spanish monarchs. He was born in Sevilla, Spain, the son of Bartolomé Ortiz de Rozas García de Villasuso and María Antonia Rodillo de Brizuela, belonging to a noble family from Santander. He began his military career as a cadet in the "Guardias de Corps", a special infantry corps created to serve as custodians of the Spanish monarchs.