The Downtown Winters Historic District, also known as the Main Street Historic District, is a historic district in Winters, Yolo County, California which includes the block of Main Street between Railroad Avenue and First Street. The district is the commercial center of Winters and includes commercial buildings built between the 1870s and 1912. Twenty buildings are included in the district, thirteen of which are contributing buildings. The most prominent building in the district is the DeVilbiss Hotel, which was built in 1899 and designed by of Sacramento. The Bank of Winters Business Block, a 1904 structure located across from the hotel, is also considered a centerpiece of the district. Two buildings in the district date from the founding of Winters in the mid-1870s: the Opera House and