Drug barons of Colombia refer to some of the most notable drug lords which operate in illegal drug trafficking in Colombia. Several of them, notably Pablo Escobar, were long considered among the world's most dangerous and most wanted men by U.S. intelligence. "Ruthless and immensely powerful", several political leaders, such as President Virgilio Barco Vargas, became convinced that the drug lords were becoming so powerful that they could oust the formal government and run the country.