EIF1
Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. eIF1 interacts with the eukaryotic small (40S) ribosomal subunit and eIF3, and is a component of the 43S preinitiation complex (PIC). eIF1 and eIF1A bind cooperatively to the 40S to stabilize an "open" conformation of the preinitiation complex (PIC) during eukaryotic translation initiation. eIF1 binds to a region near the ribosomal A-site in the 40S subunit and functions in a manner similar to the structurally related bacterial counterpart IF1.
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43S preinitiation complexEIF-W2 protein domainEIF1 (gene)EIF2Eukaryotic initiation factorEukaryotic initiation factor 3Eukaryotic ribosomeEukaryotic small ribosomal subunit (40S)Hepatitis C virus internal ribosome entry siteHousekeeping geneInitiation factorInternal ribosome entry siteKozak consensus sequenceList of human protein-coding genes 1RibosomeSUI1
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EIF1
Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. eIF1 interacts with the eukaryotic small (40S) ribosomal subunit and eIF3, and is a component of the 43S preinitiation complex (PIC). eIF1 and eIF1A bind cooperatively to the 40S to stabilize an "open" conformation of the preinitiation complex (PIC) during eukaryotic translation initiation. eIF1 binds to a region near the ribosomal A-site in the 40S subunit and functions in a manner similar to the structurally related bacterial counterpart IF1.
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Eukaryotic translation initiat ...... ted bacterial counterpart IF1.
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Eukaryotic translation initiat ...... ted bacterial counterpart IF1.
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EIF1
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