EZH2
Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates heterochromatin formation thereby silences gene function. Remodeling of chromosomal heterochromatin by EZH2 is also required during cell mitosis.
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3-Deazaneplanocin AATRXChromosome 7Chronic myelomonocytic leukemiaDiffuse large B-cell lymphomaEZH1EZH2 (gene)Enhancer of zesteEpigenetic regulation of neurogenesisEpigenetics of diabetes Type 2Epigenetics of human developmentEpithelioid sarcomaEzh2Ezh2 geneFollicular lymphomaHDAC1HOXA11-AS1HSV epigeneticsHistone deacetylase 2Histone methyltransferaseImidazopyridineIn situ lymphoid neoplasiaInflammationList of human protein-coding genes 2Mdm2MiR-138Mir-26 microRNA precursor familyO-GlcNAcPolycomb-group proteinsPolycomb protein EEDRAD51CSET domainSTAT5TazemetostatThomas JenuweinVAV1Weaver syndromeXRCC2XRCC3Yi Zhang (biochemist)
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EZH2
Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates heterochromatin formation thereby silences gene function. Remodeling of chromosomal heterochromatin by EZH2 is also required during cell mitosis.
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Enhancer of zeste homolog 2 (E ...... sorder, ataxia telangiectasia.
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Histone-lysine N-methyltransferase
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Enhancer of zeste homolog 2 (E ...... required during cell mitosis.
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EZH2
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