Ectopoglossus lacrimosus is a species of frog in the family Dendrobatidae. It is endemic to western Colombia where it is known from the drainage of Atrato River, San Juan River, and . It is a very rare frog found along streams in lowland and foothill forests and may be declining from threats such as deforestation for agriculture (including illegal crops), logging, human settlement and pollution from spraying of illegal crops. The only conservation measure known is that it occurs in Parque Nacional Natural Farallones de Cali.