Eileen Donoghue (born 1954 in Holyoke, Massachusetts) is the city manager of Lowell, Massachusetts. She is a former member of the Massachusetts Senate, where she has represented the First Middlesex District from 2011 to 2018, as well as a former city councilor (1996–2008) and mayor (1998–2002) of Lowell. She ran in the Massachusetts' 5th Congressional District special election in 2007 to fill the United States House of Representatives seat vacated by Marty Meehan, narrowly losing the Democratic primary to Niki Tsongas. In the Massachusetts Senate, Donoghue has been a staunch advocate for small businesses, economic development in gateway cities, and public higher education. She has spearheaded efforts to reduce student loan debt and create pathways to stable jobs.