Estriol glucuronide
Estriol glucuronide (E3G), or oestriol glucuronide, also known as estriol monoglucuronide, as well as estriol 16α-β-D-glucosiduronic acid, is a natural, steroidal estrogen and the glucuronic acid (β-D-glucopyranuronic acid) conjugate of estriol. It occurs in high concentrations in the urine of pregnant women as a reversibly formed metabolite of estriol. Estriol glucuronide is a prodrug of estriol, and was the major component of Progynon and Emmenin, estrogenic products manufactured from the urine of pregnant women that were introduced in the 1920s and 1930s and were the first orally active estrogens. Emmenin was succeeded by Premarin (conjugated equine estrogens), which is sourced from the urine of pregnant mares and was introduced in 1941. Premarin replaced Emmenin due to the fact that it
C24H32O9Conjugated estriolConjugated estrogensEstradiol 3-glucuronideEstradiol glucuronide1,2-dimethoxyethaanEstriol_(medication)Estriol 16α-glucuronideEstriol 3-glucuronideEstriol monoglucuronideEstriol sulfateEstriol sulfate glucuronideEstrogenEstrogen (medication)Estrogen conjugateEstrone glucuronideEstrone sulfateList of estrogen estersOestriol glucuronideOestriol monoglucuronide
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Estriol glucuronide
Estriol glucuronide (E3G), or oestriol glucuronide, also known as estriol monoglucuronide, as well as estriol 16α-β-D-glucosiduronic acid, is a natural, steroidal estrogen and the glucuronic acid (β-D-glucopyranuronic acid) conjugate of estriol. It occurs in high concentrations in the urine of pregnant women as a reversibly formed metabolite of estriol. Estriol glucuronide is a prodrug of estriol, and was the major component of Progynon and Emmenin, estrogenic products manufactured from the urine of pregnant women that were introduced in the 1920s and 1930s and were the first orally active estrogens. Emmenin was succeeded by Premarin (conjugated equine estrogens), which is sourced from the urine of pregnant mares and was introduced in 1941. Premarin replaced Emmenin due to the fact that it
has abstract
Estriol glucuronide (E3G), or ...... ch lower extent in comparison.
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CAS number
28808-07-3
PubChem
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Wikipage page ID
52,108,469
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Wikipage revision ID
992,595,637
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CAS number
ChemSpiderID
IUPAC name
PubChem
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SMILES
C[C@]12CC[C@H]3[C@H]CCC5=C3C=CCO
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StdInChI
InChI=1S/C24H32O9/c1-24-7-6-13 ...... ,18+,19-,20+,21+,23-,24+/m1/s1
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StdInChIKey
FQYGGFDZJFIDPU-JRSYHJKYSA-N
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synonyms
Estriol glucuronidate; -16,17- ...... tra-1,3,5-triene-3,16,17-triol
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Estriol glucuronide (E3G), or ...... mmenin due to the fact that it
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label
Estriol glucuronide
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