Estrone sulfamate
Estrone sulfamate (EMATE; developmental code name J994), or estrone-3-O-sulfamate, is a steroid sulfatase (STS) inhibitor which has not yet been marketed. It is the C3 sulfamate ester of the estrogen estrone. Unlike other estrogen esters however, EMATE is not an effective prodrug of estrogens. A closely related compound is estradiol sulfamate (E2MATE), which is extensively metabolized into EMATE and has similar properties to it.
primaryTopic
Estrone sulfamate
Estrone sulfamate (EMATE; developmental code name J994), or estrone-3-O-sulfamate, is a steroid sulfatase (STS) inhibitor which has not yet been marketed. It is the C3 sulfamate ester of the estrogen estrone. Unlike other estrogen esters however, EMATE is not an effective prodrug of estrogens. A closely related compound is estradiol sulfamate (E2MATE), which is extensively metabolized into EMATE and has similar properties to it.
has abstract
Estrone sulfamate (EMATE; deve ...... he treatment of endometriosis.
@en
CAS number
148672-09-7
ChEMBL
class
PubChem
Wikipage page ID
54,265,310
page length (characters) of wiki page
Wikipage revision ID
994,204,900
Link from a Wikipage to another Wikipage
CAS number
ChEMBL
ChemSpiderID
class
IUPAC name
[-13-Methyl-17-oxo-7,8,9,11,12 ...... [a]phenanthren-3-yl] sulfamate
@en
PubChem
routes of administration
SMILES
C[C@]12CC[C@H]3[C@H]CCC4=C3C=CCOSN
@en
StdInChIKey
RVKFQAJIXCZXQY-CBZIJGRNSA-N
@en
synonyms
EMATE; J994; Estrone-3-O-sulfa ...... -[oxy]estra-1,3,5-trien-17-one
@en
wikiPageUsesTemplate
comment
Estrone sulfamate (EMATE; deve ...... has similar properties to it.
@en
label
Estrone sulfamate
@en