First Baptist Church is a historic church located in Knoxville, Tennessee. It is on the National Register of Historic Places. The congregation was organized in 1843 by James and John Moses. After its first baptismal service in nearby First Creek, the church had 46 members, including 20 African-Americans. The church organized its first Sunday School in 1845. The first building was constructed on Gay Street in 1844. The second building was built at the same location in 1887. The third (and present) building was completed in 1923 at the Main Street location, three years after Dr. Frederick Fernando Brown became pastor. This architecturally-significant structure, noteworthy for its Neoclassical design and octagonal sanctuary, was designed by Dougherty & Gardner of Nashville, Tennessee, and is