The First Battle of Newtonia Historic District, near Newtonia, Missouri, is a National Register of Historic Places (NRHP) site that preserves the location of the First Battle of Newtonia, an 1862 battle during the American Civil War. The battle saw Confederate troops under Colonels Douglas H. Cooper and Joseph O. Shelby defeat a Union force commanded by Brigadier General Frederick Salomon. The historic district contains some Civil War-period structures, as well as the Mathew H. Ritchey House, which is listed separately on the NRHP.