Fluasterone
Fluasterone, also known as 3β-dehydroxy-16α-fluoro-DHEA or 16α-fluoroandrost-5-en-17-one, is a fluorinated synthetic analogue of dehydroepiandrosterone (DHEA) which was under investigation by Aeson Therapeutics for a variety of therapeutic indications including cancer, cardiovascular diseases, diabetes, obesity, and traumatic brain injury among others but was ultimately never marketed. It is a modification of DHEA in which the C3β hydroxyl has been removed and a hydrogen atom has been substituted with a fluorine atom at the C16α position. Fluasterone reached phase II clinical trials prior to the discontinuation of its development.
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Fluasterone
Fluasterone, also known as 3β-dehydroxy-16α-fluoro-DHEA or 16α-fluoroandrost-5-en-17-one, is a fluorinated synthetic analogue of dehydroepiandrosterone (DHEA) which was under investigation by Aeson Therapeutics for a variety of therapeutic indications including cancer, cardiovascular diseases, diabetes, obesity, and traumatic brain injury among others but was ultimately never marketed. It is a modification of DHEA in which the C3β hydroxyl has been removed and a hydrogen atom has been substituted with a fluorine atom at the C16α position. Fluasterone reached phase II clinical trials prior to the discontinuation of its development.
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Fluasterone, also known as 3β- ...... t unsuitable for clinical use.
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CAS number
112859-71-9
FDA UNII code
R7M5UGD04G
PubChem
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54,196,760
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994,292,240
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ChemSpiderID
IUPAC name
PubChem
SMILES
C[C@]12CCCCC1=CC[C@@H]3[C@@H]2CC[C@]4C
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StdInChIKey
VHZXNQKVFDBFIK-NBBHSKLNSA-N
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UNII
R7M5UGD04G
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Fluasterone, also known as 3β- ...... ntinuation of its development.
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label
Fluasterone
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