Frank Gamble (born 1871, date of death unknown) was a footballer who played in The Football League as an inside forward for Sheffield United. Born in Worksop in Nottinghamshire, Gamble was playing for Sheffield side Heeley when he came to the attention of Sheffield United. United had just been accepted into the newly formed Second Division and registered Gamble as a guest player for the 1892–93 season. He made little impact, spending most of his time either in the reserves or playing for his parent club, making only one competitive start for the Blades in a Northern League fixture against Stockton.