Franklin-Colonial is a Roanoke, Virginia neighborhood located in southwest Roanoke that is bisected by the three primary arterials of Franklin Road, the Roy L. Webber Expressway and Colonial Avenue. It borders the neighborhoods of Wasena and South Jefferson to the north, Grandin Court and Raleigh Court to the west and South Roanoke to the east. The southern border is shared with Roanoke County. As of the 2000 U.S. Census, Franklin-Colonial had a total population of 2,860.