Functional magnetic resonance spectroscopy of the brain (fMRS) uses magnetic resonance imaging (MRI) to study brain metabolism during brain activation. The data generated by fMRS usually shows spectra of resonances, instead of a brain image, as with MRI. The area under peaks in the spectrum represents relative concentrations of metabolites. The main goals of fMRS studies are to contribute to the understanding of energy metabolism in the brain, and to test and improve data acquisition and quantification techniques to ensure and enhance validity and reliability of fMRS studies.