Galeotto II Pico della Mirandola, lord of Mirandola (Mirandola, 1508 - Paris, 20 November 1550), was an Italian condottiere. He was the son of , who died in 1509 and and grew under the tutelage of his mother, who ruled the state in his name until 1511. He learned from it the hatred of his uncle Gianfrancesco II Pico, lord of Mirandola. In 1533 he entered the castle and murdered his uncle, taking power. Then Emperor Charles V sent his commissioners to Mirandola, inviting Galeotto to hand over the State, but he refused and was therefore sentenced to death. But not even the sending of the general Antonio de Leyva succeeded in moving Galeotto.