GlmS glucosamine-6-phosphate activated ribozyme
The glucosamine-6-phosphate riboswitch ribozyme ( glmS ribozyme) is an RNA structure that resides in the 5' untranslated region (UTR) of the mRNA transcript of the glmS gene. This RNA regulates the glmS gene by responding to concentrations of a specific metabolite, glucosamine-6-phosphate (GlcN6P), in addition to catalyzing a self-cleaving chemical reaction upon activation. This cleavage leads to the degradation of the mRNA that contains the ribozyme, and lowers production of GlcN6P. The glmS gene encodes for an enzyme glutamine-fructose-6-phosphate amidotransferase, which catalyzes the formation of GlcN6P, a compound essential for cell wall biosynthesis, from fructose-6-phosphate and glutamine. Thus, when GlcN6P levels are high, the glmS ribozyme is activated and the mRNA transcript is de
Link from a Wikipage to another Wikipage
primaryTopic
GlmS glucosamine-6-phosphate activated ribozyme
The glucosamine-6-phosphate riboswitch ribozyme ( glmS ribozyme) is an RNA structure that resides in the 5' untranslated region (UTR) of the mRNA transcript of the glmS gene. This RNA regulates the glmS gene by responding to concentrations of a specific metabolite, glucosamine-6-phosphate (GlcN6P), in addition to catalyzing a self-cleaving chemical reaction upon activation. This cleavage leads to the degradation of the mRNA that contains the ribozyme, and lowers production of GlcN6P. The glmS gene encodes for an enzyme glutamine-fructose-6-phosphate amidotransferase, which catalyzes the formation of GlcN6P, a compound essential for cell wall biosynthesis, from fructose-6-phosphate and glutamine. Thus, when GlcN6P levels are high, the glmS ribozyme is activated and the mRNA transcript is de
has abstract
The glucosamine-6-phosphate ri ...... ing a bioinformatics approach.
@en
Wikipage page ID
11,420,863
page length (characters) of wiki page
Wikipage revision ID
992,559,444
Link from a Wikipage to another Wikipage
caption
Predicted secondary structure and sequence conservation of glmS
@en
id
RF00234
@en
name
glmS glucosamine-6-phosphate activated ribozyme
@en
Rfam
RF00234
@en
RNA type
symbol
glmS
@en
Tax domain
wikiPageUsesTemplate
hypernym
type
comment
The glucosamine-6-phosphate ri ...... and the mRNA transcript is de
@en
label
GlmS glucosamine-6-phosphate activated ribozyme
@en