HLA-DR
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human Leukocyte Antigen – DR isotype ) and peptide, generally between 9 and 30 amino acids in length, constitutes a ligand for the T-cell receptor (TCR). HLA (human leukocyte antigens) were originally defined as cell surface antigens that mediate graft-versus-host disease. Identification of these antigens has led to greater success and longevity in organ transplant.
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A30-Cw5-B18-DR3-DQ2_(HLA_Haplotype)Acute generalized exanthematous pustulosisAcute myeloid leukemiaApolizumabB-cell prolymphocytic leukemiaCFU-GEMMChromosome 6Chronic myelomonocytic leukemiaDeliriumDrug reaction with eosinophilia and systemic symptomsEftilagimod alphaGraft-versus-host diseaseHLA-DPHLA-DQHLA-DQ7HLA-DR1HLA-DR10HLA-DR11HLA-DR12HLA-DR13HLA-DR14HLA-DR15HLA-DR16HLA-DR17HLA-DR18HLA-DR2HLA-DR3HLA-DR4HLA-DR51HLA-DR52HLA-DR53HLA-DR7HLA-DR8HLA-DR9HLA-DRAHLA-DRB1HLA-DRB3HLA-DRB4HLA-DRB5HLA-DR antigens
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HLA-DR
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human Leukocyte Antigen – DR isotype ) and peptide, generally between 9 and 30 amino acids in length, constitutes a ligand for the T-cell receptor (TCR). HLA (human leukocyte antigens) were originally defined as cell surface antigens that mediate graft-versus-host disease. Identification of these antigens has led to greater success and longevity in organ transplant.
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HLA-DR is an MHC class II cell ...... mulating B-cell proliferation.
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1,018,108,729
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Immune recognition and
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antigen presentation
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heteropolymer
MHC class II, DR
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Illustration of DR with bound ligand
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Chromosome 6p21.31
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heterodimer
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HLA-DR is an MHC class II cell ...... longevity in organ transplant.
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HLA-DR
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