Hamden Slough National Wildlife Refuge is a National Wildlife Refuge of the United States in Minnesota. Eastern hardwood forests stretching from the Atlantic seaboard give way to the western prairie at the area, in Audubon Township, near Audubon, Minnesota. Prior to settlement, its diverse vegetation was attractive to wildlife: waterfowl, upland birds, bison, wolves, and other prairie wildlife. When fully restored, the refuge will provide the largest contiguous block of wetland prairie habitat in the region, encompassing nearly 6,000 acres (24 km2).