Hanover Lutheran Church is a Lutheran congregation in Cape Girardeau, Missouri, that is a member of the Lutheran Church–Missouri Synod. The congregation's original organization came about in 1846 as a result of the heavy German immigration to Missouri in the 19th century. The church's name, "Hanover", was chosen to reflect the place of origin of the majority of its members, since many of the Germans who had settled northwest of the town of Cape Girardeau had immigrated from Hanover, Germany.