Heleen Margriet Dupuis (born 30 May 1945) is a Dutch ethicist, professor, and politician who served in the Senate from 1999 to 2015 as part of the People's Party for Freedom and Democracy (VVD). Her father was a doctor with a practice out of her hometown of Rotterdam. She began her professional career as a part-time teacher and professor in the 1970s. From there, she worked in the ethics department at Leiden University. She served as chairman of the Dutch Voluntary Euthanasia Association from 1981 to 1985, and has also served as chairman of the Alzheimer's Council of the Netherlands; she cites the death of her first husband from dementia in her support of voluntary euthanasia.