The Hokkaidō Development Commission (開拓使, Kaitakushi), sometimes referred to as Hokkaidō Colonization Office or simply Kaitakushi, was a government agency in early Meiji Japan. Tasked with the administration, economic development, and securing of the northern frontier in what, at the time of establishment, was known as Ezo, it was established in 1869 and disbanded in 1882.