Hydroxyprogesterone caproate
Hydroxyprogesterone caproate (OHPC), sold under the brand names Proluton and Makena among others, is a progestin medication which is used to prevent preterm birth in pregnant women with a history of the condition and to treat gynecological disorders. It has also been formulated in combination with estrogens for various indications (brand names Gravibinon and Primosiston) and as a form of long-lasting injectable birth control (brand name Chinese Injectable No. 1). It is not used by mouth and is instead given by injection into muscle or fat, typically once per week to once per month depending on the indication.
17-Hydroxyprogesterone caproate17-Hydroxyprogesterone capronate17-alpha-Hydroxy-progesterone caproate17-alpha-Hydroxyprogesterone caproate17-alpha-hydroxy-progesterone caproate17-alpha-hydroxyprogesterone caproate17-hydroxyprogesterone caproate17-hydroxyprogesterone capronate17α-Hydroxyprogesterone caproate17α-Hydroxyprogesterone capronate17α-hydroxyprogesterone caproate17α-hydroxyprogesterone capronateDelalutinGestagenoHydroxyprogesterone capronateHydroxyprogesterone hexanoateLPCN-1107LPCN1107LPCN 1107OHPCPherlon
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17-Hydroxyprogesterone caproate17-Hydroxyprogesterone capronate17-alpha-Hydroxy-progesterone caproate17-alpha-Hydroxyprogesterone caproate17-alpha-hydroxy-progesterone caproate17-alpha-hydroxyprogesterone caproate17-hydroxyprogesterone caproate17-hydroxyprogesterone capronate1,2-dimethoxyethaan17α-Hydroxyprogesterone caproate17α-Hydroxyprogesterone capronate17α-Methylprogesterone17α-hydroxyprogesterone caproate17α-hydroxyprogesterone capronateATC code G03Algestone acetophenideAllylestrenolAntiandrogenC27H40O41,2-dimethoxyethaanChlormadinone_acetateChlormadinone caproateCombined injectable birth controlCyproterone_acetateDelalutinDelmadinone acetateDiethylstilbestrolEndometrial cancerEstradiol_(medication)Estradiol_benzoateEstradiol benzoate/estradiol valerate/hydroxyprogesterone caproateEstradiol benzoate/hydroxyprogesterone caproateEstradiol benzoate/progesteroneEstradiol cypionate/hydroxyprogesterone caproateEstradiol dipropionateEstradiol dipropionate/hydroxyprogesterone caproateEstradiol hexahydrobenzoateEstradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoateEstradiol_valerateEstradiol valerate/gestonorone caproate
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Hydroxyprogesterone caproate
Hydroxyprogesterone caproate (OHPC), sold under the brand names Proluton and Makena among others, is a progestin medication which is used to prevent preterm birth in pregnant women with a history of the condition and to treat gynecological disorders. It has also been formulated in combination with estrogens for various indications (brand names Gravibinon and Primosiston) and as a form of long-lasting injectable birth control (brand name Chinese Injectable No. 1). It is not used by mouth and is instead given by injection into muscle or fat, typically once per week to once per month depending on the indication.
has abstract
Hydroxyprogesterone caproate ( ...... his became prohibited in 2016.
@en
L'idrossiprogesterone caproato ...... sterilizzate con calore secco.
@it
Le caproate d'hydroxyprogestér ...... s cela a été interdit en 2016.
@fr
هيدروكسي بروجستيرون كابرويت (ب ...... دام الطبي في عامي 1954 و 1955.
@ar
alternative name
Delalutin, Proluton, Proluton Depot, Makena, others
@en
CAS number
FDA UNII code
276F2O42F5
PubChem
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Wikipage page ID
10,084,734
page length (characters) of wiki page
Wikipage revision ID
1,010,130,218
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ATC prefix
G03
@en
ATC suffix
DA03
@en
bioavailability
Intramuscular: 100%
@en
Oral: Very low
@en
CAS number
ChemSpiderID
elimination half-life
-1468800.0
excretion
Feces: 50%
@en
Urine: 30%
@en
image
@en
IUPAC name
[-17-acetyl-10,13-dimethyl-3-o ...... a]phenanthren-17-yl] hexanoate
@en
metabolism
Reduction and hydroxylation and conjugation
@en
pregnancy US
B
@en
protein bound
Extensive
@en
PubChem
routes of administration
• Intramuscular injection
@en
• Subcutaneous autoinjection
@en
SMILES
O=C4\C=C2/[C@]CC4
@en
StdInChIKey
DOMWKUIIPQCAJU-LJHIYBGHSA-N
@en
synonyms
OHPC; Hydroxyprogesterone capr ...... 4-ene-3,20-dione 17α-hexanoate
@en
tradename
Delalutin, Proluton, Proluton Depot, Makena, others
@en
Verifiedfields
verified
@en
verifiedrevid
477,198,932
wikiPageUsesTemplate
subject
hypernym
comment
Hydroxyprogesterone caproate ( ...... h depending on the indication.
@en
L'idrossiprogesterone caproato ...... della stimolazione estrogena)
@it
Le caproate d'hydroxyprogestér ...... s par mois selon l'indication.
@fr
هيدروكسي بروجستيرون كابرويت (ب ...... مركبات البروجستيرونية الاصطناع
@ar
label
Hydroxyprogesterone caproate
@en
Hydroxyprogestérone caproate
@fr
Idrossiprogesterone caproato
@it
هيدروكسي بروجستيرون كابرويت
@ar