Infected cell protein 34.5
Infected cell protein 34.5 (ICP-34.5, ICP34.5, or GADD34) is a protein expressed by the ɣ34.5 gene in viruses such as herpes simplex virus; it blocks a cellular stress response to viral infection. It shares the C-terminal regulatory domain (InterPro: IPR019523) with protein phosphatase 1 subunit 15A/. The ICP34.5 deletion is useful for the construction of Oncolytic herpes viruses, as cancer cells do not restrict replication as strongly.
Wikipage redirect
Link from a Wikipage to another Wikipage
primaryTopic
Infected cell protein 34.5
Infected cell protein 34.5 (ICP-34.5, ICP34.5, or GADD34) is a protein expressed by the ɣ34.5 gene in viruses such as herpes simplex virus; it blocks a cellular stress response to viral infection. It shares the C-terminal regulatory domain (InterPro: IPR019523) with protein phosphatase 1 subunit 15A/. The ICP34.5 deletion is useful for the construction of Oncolytic herpes viruses, as cancer cells do not restrict replication as strongly.
has abstract
Infected cell protein 34.5 (IC ...... trict replication as strongly.
@en
Wikipage page ID
52,007,407
page length (characters) of wiki page
Wikipage revision ID
996,335,469
Link from a Wikipage to another Wikipage
name
Neurovirulence factor ICP34.5
@en
Organism
Human alphaherpesvirus 1 strain 17
@en
symbol
ICP34.5
@en
UniProt
P36313
@en
wikiPageUsesTemplate
subject
comment
Infected cell protein 34.5 (IC ...... trict replication as strongly.
@en
label
Infected cell protein 34.5
@en