Isaac Parsons (January 27, 1752 – August 25, 1796) was an American slave owner, politician, and militia officer in the U.S. state of Virginia (now West Virginia). Parsons served as a member of the Virginia House of Delegates representing Hampshire County from 1789 until his death in 1796. Following an act of the Virginia General Assembly in 1789, Parsons was appointed to serve as a trustee for the town of Romney. In 1790, Parsons began serving as a justice for Hampshire County. He served as a captain in command of a company in the Virginia militia during the American Revolutionary War and continued to serve as a captain in the Hampshire County militia following the war. Parsons operated a public ferry across the South Branch Potomac River, and later died from drowning in the river in 1796.