JWH-051
JWH-051 is an analgesic drug which is a cannabinoid agonist. Its chemical structure is closely related to that of the potent cannabinoid agonist HU-210, with the only difference being the removal of the hydroxyl group at position 1 of the aromatic ring. It was discovered and named after John W. Huffman. JWH-051 retains high affinity for the CB1 receptor, but is a much stronger agonist for CB2, with a Ki value of 14nM at CB2 vs 19nM at CB1. It was one of the first CB2-selective ligands developed, although its selectivity for CB2 is modest compared to newer compounds such as HU-308.
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JWH-051
JWH-051 is an analgesic drug which is a cannabinoid agonist. Its chemical structure is closely related to that of the potent cannabinoid agonist HU-210, with the only difference being the removal of the hydroxyl group at position 1 of the aromatic ring. It was discovered and named after John W. Huffman. JWH-051 retains high affinity for the CB1 receptor, but is a much stronger agonist for CB2, with a Ki value of 14nM at CB2 vs 19nM at CB1. It was one of the first CB2-selective ligands developed, although its selectivity for CB2 is modest compared to newer compounds such as HU-308.
has abstract
JWH-051 is an analgesic drug w ...... to its strong activity at CB2.
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JWH-051 – organiczny związek c ...... aktywności w stosunku do CB2.
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PubChem
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17,284,718
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993,948,335
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ChemSpiderID
IUPAC name
methanol
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PubChem
SMILES
CCCCCCCC1=CC2=C[C@@H]3CCCO
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StdInChIKey
ORTVDISIJXKUAV-FCHUYYIVSA-N
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Verifiedfields
changed
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verifiedrevid
424,831,591
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changed
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wikiPageUsesTemplate
hypernym
comment
JWH-051 is an analgesic drug w ...... ewer compounds such as HU-308.
@en
JWH-051 – organiczny związek c ...... aktywności w stosunku do CB2.
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label
JWH-051
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JWH-051
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