Jesse (or Jessua) Smythes (died 1594) was an English born judge and colonist in Elizabethan Ireland. He held office as Solicitor General for Ireland and Chief Justice of Munster, and was heavily involved in the Plantation of Munster. He was noted for his deep hostility to the native Irish, which was even more virulent than that of the average English colonist of the time. The English Government was informed of his recent death in January 1594. William Saxey succeeded him as Chief Justice of Munster.