John G. Webb, M.D., FRCPC is a Canadian interventional cardiologist and the McLeod Professor of Heart Valve Intervention at the University of British Columbia. He is most well known for performing the first transfemoral and the first transapical transcatheter aortic valve implantation in the world both in 2005. He completed the first ever transcatheter mitral valve-in-valve replacement in 2009 and the first in-human TMVR (transcatheter mitral valve replacement) to be completed with the Neovasc Tiara device in 2014. In addition, he was an investigator in the PARTNER trial, a randomized clinical trial demonstrating the efficacy of TAVI compared to aortic valve replacement and medical intervention.