Joseph S. Manasse (August 3, 1831 – December 26, 1897) was an early settler of San Diego, California. Manasse was born in 1831 in Filehne, Prussia and came to San Diego in 1853 with his brother Heyman and cousin Moses. He opened a store in Old Town San Diego with little money, but soon prospered. In 1856, he formed a long-time partnership with Marcus Schiller, who was called a "Jewish Horatio Alger" by a biographer. They ran a large general store, J. S. Manasse and Company. They bought a lumberyard at the foot of E Street in 1868, and were the first to bring lumber ships into San Diego Bay. Soon afterward, they bought Rancho Los Encinitos, in present Encinitas, and raised cattle there. They also owned a 160-acre (0.65 km2) farm. They built up a large business, but suffered severely in the