Katherine Brunett McGuire is an American political aide and government official who served as the Assistant Secretary of Labor for Congressional and Intergovernmental Affairs. Prior to her confirmation, she was the chief of staff to U.S. Representative Randy Hultgren. McGuire previously served as staff director of the United States Senate Committee on Health, Education, Labor and Pensions under Mike Enzi. She also served as Enzi's legislative director and as staff director of the United States Senate Committee on Banking, Housing, and Urban Affairs. She has held posts with Alan K. Simpson and Richard Lugar. McGuire's private sector experience includes leading BSA (The Software Alliance)'s global public policy and government relations division as vice president.