The Kokolik River (Iñupiaq: Qaqalik) is a stream, 200 miles (320 km) long, in the western North Slope of the U.S. state of Alaska. It rises in the De Long Mountains of the western Brooks Range and flows generally north and northwest into the Kasegaluk Lagoon. The river mouth is 1 mile (1.6 km) east of Point Lay, on the Chukchi Sea of the Arctic Ocean. Its Inuit name, Qaqalik, refers to the alpine bistort, an edible plant found in the region. A variant name, Kepizetka (qipigsatqaq), recorded on an Inuit map in the late 19th century, means "it twists" or "crooked".