LR-5182
LR-5182 is a stimulant drug which acts as a norepinephrine–dopamine reuptake inhibitor, structurally related to the better known drug fencamfamine. It was developed by the pharmaceutical company Eli Lilly in the 1970s, and researched for potential use as an antidepressant, although never marketed. LR-5182 has two stereoisomers, both of which are active, although one isomer blocks reuptake of only dopamine and noradrenaline, while the other blocks reuptake of serotonin as well. is planar and contains a Bicyclo-octene. This itself is fully active: DA 9nM, NE 27nM, SER 0.6 μM.
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LR-5182
LR-5182 is a stimulant drug which acts as a norepinephrine–dopamine reuptake inhibitor, structurally related to the better known drug fencamfamine. It was developed by the pharmaceutical company Eli Lilly in the 1970s, and researched for potential use as an antidepressant, although never marketed. LR-5182 has two stereoisomers, both of which are active, although one isomer blocks reuptake of only dopamine and noradrenaline, while the other blocks reuptake of serotonin as well. is planar and contains a Bicyclo-octene. This itself is fully active: DA 9nM, NE 27nM, SER 0.6 μM.
has abstract
LR-5182 is a stimulant drug wh ...... : DA 9nM, NE 27nM, SER 0.6 μM.
@en
CAS number
62373-97-1
ChEMBL
PubChem
Wikipage page ID
17,648,221
page length (characters) of wiki page
Wikipage revision ID
1,001,101,535
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CAS number
ChEMBL
ChemSpiderID
index2 label
HCl
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IUPAC name
SMILES
CNC[C@@H]1C2CCC[C@@H]1c3ccccc3
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[Cl-].C[NH+]C[C@@H]1C2CCC[C@@H]1c3ccccc3
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StdInChIKey
CWRRQXXGIKGNJA-PQTJMFGHSA-N
@en
JOQQHMGSIKNGAF-HLFYOVGASA-N
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synonyms
-LR-5182, -LR-5182 hydrochloride
@en
verifiedrevid
415,309,432
wikiPageUsesTemplate
subject
hypernym
comment
LR-5182 is a stimulant drug wh ...... : DA 9nM, NE 27nM, SER 0.6 μM.
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label
LR-5182
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