Ladostigil
Ladostigil (TV-3,326) is a novel neuroprotective agent being investigated for the treatment of neurodegenerative disorders like Alzheimer's disease, Lewy body disease, and Parkinson's disease. It acts as a reversible acetylcholinesterase and butyrylcholinesterase inhibitor, and an irreversible monoamine oxidase B inhibitor, and combines the mechanisms of action of older drugs like rivastigmine and rasagiline into a single molecule. In addition to its neuroprotective properties, ladostigil enhances the expression of neurotrophic factors like GDNF and BDNF, and may be capable of reversing some of the damage seen in neurodegenerative diseases via the induction of neurogenesis. Ladostigil also has antidepressant effects, and may be useful for treating comorbid depression and anxiety often seen
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Ladostigil
Ladostigil (TV-3,326) is a novel neuroprotective agent being investigated for the treatment of neurodegenerative disorders like Alzheimer's disease, Lewy body disease, and Parkinson's disease. It acts as a reversible acetylcholinesterase and butyrylcholinesterase inhibitor, and an irreversible monoamine oxidase B inhibitor, and combines the mechanisms of action of older drugs like rivastigmine and rasagiline into a single molecule. In addition to its neuroprotective properties, ladostigil enhances the expression of neurotrophic factors like GDNF and BDNF, and may be capable of reversing some of the damage seen in neurodegenerative diseases via the induction of neurogenesis. Ladostigil also has antidepressant effects, and may be useful for treating comorbid depression and anxiety often seen
has abstract
Ladostigil (TV-3,326) is a nov ...... seen in such diseases as well.
@en
ラドスチギル(Ladostigil)は、アルツハイマー病やレ ...... よく見られるうつと不安の併発の治療にも効果が期待されている。
@ja
CAS number
209349-27-4
FDA UNII code
SW3H1USR4Q
KEGG
PubChem
Wikipage page ID
25,278,076
page length (characters) of wiki page
Wikipage revision ID
992,162,607
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ATC prefix
None
@en
CAS number
ChemSpiderID
IUPAC name
[-3-indan-5-yl]-N-propylcarbamate
@en
KEGG
D03239
@en
legal status
Uncontrolled
@en
PubChem
routes of administration
Oral
@en
synonyms
[N-propargyl--aminoindan-5yl]-N-propylcarbamate
@en
UNII
SW3H1USR4Q
@en
wikiPageUsesTemplate
subject
hypernym
comment
Ladostigil (TV-3,326) is a nov ...... ression and anxiety often seen
@en
ラドスチギル(Ladostigil)は、アルツハイマー病やレ ...... よく見られるうつと不安の併発の治療にも効果が期待されている。
@ja
label
Ladostigil
@en
ラドスチギル
@ja