Lake Oponona (Ndonga: the one that swallowed up all the water) is a natural lake in the Uuvudhiya Constituency in the Oshana Region of northern Namibia. It is situated about 70 kilometres (43 mi) from Etosha Pan and is the largest lake in the . It holds water up to the following rainy season in a prosperous year. Because the lake maintains water for a long time a number of birds like flamingos and others temporarily move there when the oshanas (flood plains), swamps, and other wetlands dry up. There is also Oponona River situated at village of Ompundja Constituency.