Leimgruber–Batcho indole synthesis
The Leimgruber–Batcho indole synthesis is a series of organic reactions that produce indoles from o-nitrotoluenes 1. The first step is the formation of an enamine 2 using N,N-dimethylformamide dimethyl acetal and pyrrolidine. The desired indole 3 is then formed in a second step by reductive cyclisation. In the above scheme, the reductive cyclisation is effected by Raney nickel and hydrazine. Palladium-on-carbon and hydrogen, stannous chloride, sodium hydrosulfite, or iron in acetic acid are also effective reducing agents.
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Leimgruber–Batcho indole synthesis
The Leimgruber–Batcho indole synthesis is a series of organic reactions that produce indoles from o-nitrotoluenes 1. The first step is the formation of an enamine 2 using N,N-dimethylformamide dimethyl acetal and pyrrolidine. The desired indole 3 is then formed in a second step by reductive cyclisation. In the above scheme, the reductive cyclisation is effected by Raney nickel and hydrazine. Palladium-on-carbon and hydrogen, stannous chloride, sodium hydrosulfite, or iron in acetic acid are also effective reducing agents.
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De Leimgruber-Batcho-indoolsyn ...... actieomstandigheden mild zijn.
@nl
Die Batcho-Leimgruber-Indol-Sy ...... 971 das erste Mal berichteten.
@de
La synthèse d'indole de Leimgr ...... cialement ou aisés à préparer.
@fr
La síntesis de indoles de Leim ...... agentes reductores efectivos.
@es
Leimgruber-Batcho吲哚合成（Leimgrub ...... 化亚锡、连二亚硫酸钠 以及铁-乙酸 都可用作还原一步的试剂。
@zh
Leimgruberova–Batchova syntéza ...... ztok železa v kyselině octové.
@cs
The Leimgruber–Batcho indole s ...... lso effective reducing agents.
@en
Реакция Лемгрубера — Бачо — си ...... или железо в уксусной кислоте.
@ru
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De Leimgruber-Batcho-indoolsyn ...... esponderende indool 3 gebeurt.
@nl
Die Batcho-Leimgruber-Indol-Sy ...... 971 das erste Mal berichteten.
@de
La synthèse d'indole de Leimgr ...... contient des dérivés indolés.
@fr
La síntesis de indoles de Leim ...... agentes reductores efectivos.
@es
Leimgruber-Batcho吲哚合成（Leimgrub ...... 化亚锡、连二亚硫酸钠 以及铁-乙酸 都可用作还原一步的试剂。
@zh
Leimgruberova–Batchova syntéza ...... ztok železa v kyselině octové.
@cs
The Leimgruber–Batcho indole s ...... lso effective reducing agents.
@en
Реакция Лемгрубера — Бачо — си ...... или железо в уксусной кислоте.
@ru
label
Batcho-Leimgruber-Indol-Synthese
@de
Leimgruber-Batcho-indoolsynthese
@nl
Leimgruber-Batcho吲哚合成
@zh
Leimgruberova–Batchova syntéza indolů
@cs
Leimgruber–Batcho indole synthesis
@en
Synthèse d'indole de Leimgruber-Batcho
@fr
Síntesis de indoles de Leimgruber–Batcho
@es
Реакция Лемгрубера — Бачо
@ru