Levoketoconazole
Levoketoconazole (INN, USAN) (developmental code name COR-003; tentative brand name Recorlev, previously NormoCort), also known as (2S,4R)-ketoconazole, is a steroidogenesis inhibitor that is under development by Strongbridge Biopharma (formerly Cortendo AB) for the treatment of Cushing's syndrome. It is currently in phase III clinical trials for this indication. The drug is the levorotatory or (2S,4R) enantiomer of ketoconazole. It is expected to have greater potency, efficacy, and safety, including a lower risk of hepatotoxicity, relative to racemic ketoconazole.
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Levoketoconazole
Levoketoconazole (INN, USAN) (developmental code name COR-003; tentative brand name Recorlev, previously NormoCort), also known as (2S,4R)-ketoconazole, is a steroidogenesis inhibitor that is under development by Strongbridge Biopharma (formerly Cortendo AB) for the treatment of Cushing's syndrome. It is currently in phase III clinical trials for this indication. The drug is the levorotatory or (2S,4R) enantiomer of ketoconazole. It is expected to have greater potency, efficacy, and safety, including a lower risk of hepatotoxicity, relative to racemic ketoconazole.
has abstract
Levoketoconazole (INN, USAN) ( ...... ntly relative to ketoconazole.
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alternative name
Recorlev
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CAS number
142128-57-2
FDA UNII code
2DJ8R0NT7K
KEGG
PubChem
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Wikipage page ID
52,733,664
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Wikipage revision ID
1,015,355,692
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CAS number
ChemSpiderID
IUPAC name
KEGG
D10950
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PubChem
routes of administration
SMILES
CCN1CCNc2cccOC[C@@H]3CO[C@@]c5cccCl
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StdInChIKey
XMAYWYJOQHXEEK-ZEQKJWHPSA-N
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synonyms
COR-003; -ketoconazole; NormoCort
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tradename
Recorlev
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wikiPageUsesTemplate
subject
comment
Levoketoconazole (INN, USAN) ( ...... ative to racemic ketoconazole.
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label
Levoketoconazole
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