Lionville Historic District is a national historic district located in Uwchlan Township, Chester County, Pennsylvania, United States. The district includes 39 contributing buildings in the crossroads community of Lionville. The buildings date to the 18th and 19th century and include a variety of residential, commercial, and institutional buildings and outbuildings. Notable buildings include the Cadwalader House, Vaughan House, Red Lion Tavern (1740, 1815), Uwchlan Meeting House (1756), Wagonseller House, John Biedler Jr. Farmhouse (1811-1813), St. Paul's Parsonage (1813), Lionville Fire Company (1911), Joel Hawley Store (1834), Edith P. Moore School House and former St. Paul's Lutheran Church (now known as The Nurtury).