Isabel Lorenza (Lorencita) Ramírez de Arellano y Bartoli (July 8, 1906 – March 5, 1970) was the first wife of former Governor of Puerto Rico Luis A. Ferré and served as First Lady from 1968 until her death in 1970. In 1931, she met Luis A. Ferré and married a few months later on May 30, 1931. They had two children together: Antonio Luis and Rosario. When her husband, Ferré, won the 1968 general elections, Ramírez de Arellano assumed the role of First Lady. However, she died on March 5, 1970, one year after Ferré was sworn in.