Malonic ester synthesis
The malonic ester synthesis is a chemical reaction where diethyl malonate or another ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then converted to a substituted acetic acid. The major drawback of malonic ester synthesis is that the alkylation stage can also produce dialkylated structures. This makes separation of products difficult and yields lower.
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Acetoacetic ester synthesisAldol reactionDecarboxylationDiethyl malonateDiethyl phenylmalonateDimethyl malonateEsterEthyl acetoacetateKnoevenagel condensationKrapcho decarboxylationList of organic reactionsMalonate ester synthesis1,2-dimethoxyethaanMeldrum's acidMethylene bridgeOrganopalladiumPerkin alicyclic synthesisPhenobarbitalPotassium ethoxidePyridineSodium ethoxide
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Malonic ester synthesis
The malonic ester synthesis is a chemical reaction where diethyl malonate or another ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then converted to a substituted acetic acid. The major drawback of malonic ester synthesis is that the alkylation stage can also produce dialkylated structures. This makes separation of products difficult and yields lower.
has abstract
A síntese malônica é um tipo d ...... substituídos do ácido acético.
@pt
De malonzuurestersynthese is e ...... bonzuur wordt gesynthetiseerd.
@nl
La sintesi malonica è un tipo ...... una reazione di sostituzione.
@it
La synthèse malonique est un e ...... artir du malonate de diéthyle.
@fr
La síntesis malónica es un tip ...... ustituidos del ácido acético.
@es
The malonic ester synthesis is ...... ts difficult and yields lower.
@en
اصطناع إستر المالونيك هو تفاعل ...... جات عن بعضها ويقلل من المردود.
@ar
丙二酸酯合成（Malonic ester synthesis）是一类有机合成方法，丙二酸二乙酯或丙二酸的其他種酯類，二個羰基的α碳（直接毗鄰）烷基化，然後脱羧轉換成取代乙酸。
@zh
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1,014,962,319
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name
Malonic ester synthesis
@en
type
Coupling reaction
@en
wikiPageUsesTemplate
hypernym
type
comment
A síntese malônica é um tipo d ...... substituídos do ácido acético.
@pt
De malonzuurestersynthese is e ...... bonzuur wordt gesynthetiseerd.
@nl
La sintesi malonica è un tipo ...... una reazione di sostituzione.
@it
La synthèse malonique est un e ...... artir du malonate de diéthyle.
@fr
La síntesis malónica es un tip ...... ustituidos del ácido acético.
@es
The malonic ester synthesis is ...... ts difficult and yields lower.
@en
اصطناع إستر المالونيك هو تفاعل ...... جات عن بعضها ويقلل من المردود.
@ar
丙二酸酯合成（Malonic ester synthesis）是一类有机合成方法，丙二酸二乙酯或丙二酸的其他種酯類，二個羰基的α碳（直接毗鄰）烷基化，然後脱羧轉換成取代乙酸。
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label
Malonestersynthese
@de
Malonic ester synthesis
@en
Malonzuurestersynthese
@nl
Sintesi malonica
@it
Synthèse malonique
@fr
Síntese malônica
@pt
Síntesis malónica
@es
اصطناع إستر المالونيك
@ar
丙二酸酯合成
@zh