Manion's General Store is a historic general store and post office located at Ferndale in Sullivan County, New York. It was built before 1908 and is a large, frame building. It is two and one half stories tall, five bays wide and three bays deep, with a gable roof and deep overhanging eaves. It is built into a hillside and has a stone foundation. The store operated into the 1970s and the post office to the 1980s. It was added to the National Register of Historic Places in 2004.