Masters of Sex: The Life and Times of William Masters and Virginia Johnson, the Couple Who Taught America How to Love is a 2009 biography by Thomas Maier. The book chronicles the early lives and work of two American sexologists, Dr. William Masters and Virginia Johnson, who studied human sexuality from 1957 to the 1990s. The 2013 Showtime television series Masters of Sex, starring Michael Sheen and Lizzy Caplan, is based on the book.