Maximum androgen blockade
Maximum or maximal androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy (ADT). An example of MAB is the combination of bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) analogue such as leuprorelin or cetrorelix. MAB was developed for and is employed in the treatment of prostate cancer.
Androgen deprivation therapyAntiandrogenAspermiaCombined androgen blockadeComplete androgen blockadeCyproterone_acetateEthinylestradiol sulfonateFlutamideMaximal androgen blockadeMedical uses of bicalutamideNilutamidePharmacology of bicalutamidePharmacology of cyproterone acetatePolyestradiol_phosphateSide effects of bicalutamideSide effects of cyproterone acetateTriple androgen blockade
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Maximum androgen blockade
Maximum or maximal androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy (ADT). An example of MAB is the combination of bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) analogue such as leuprorelin or cetrorelix. MAB was developed for and is employed in the treatment of prostate cancer.
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Maximum or maximal androgen bl ...... with bicalutamide (30 to 85%).
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Maximum or maximal androgen bl ...... treatment of prostate cancer.
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Maximum androgen blockade
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